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Oncology Research/Clinical Trials Database

Frequently Asked Questions | Oncology Research/Clinical Trials Database

Title	Study/Treatment
BRAG-Onc - Medical College of Georgia Tumor Tissue and Serum Repository - Central Biorepository Alliance of Georgia-Oncology	Cancer
CALGB 30607 - Randomized, Phase III, Placebo-Controlled Trial of Sunitinib as Maintenance Therapy in Non-Progressing Pts Following an Initial Four Cycles of Platinum-Based Combination Chemotherapy in Advanced, Stage IIIB/IV Non-Small Cell Lung Cancer	Lung Cancer
CALGB 30610/RTOG0538 - Phase III Comparison of Thoracic Radiotherapy Regimens in Patients with Limited Small Cell Lung Cancer also Receiving Cisplatin and Etoposide	Lung Cancer
CALGB 80802 - PHASE III RANDOMIZED STUDY OF SORAFENIB PLUS DOXORUBICIN VERSUS SORAFENIB IN PATIENTS WIT Hadvanced hepatocellular carcinoma (HCC)	Hepatocellular Cancer
CALGB 90601 - A Randomized Doubled-Blinded Phase III Study Comparing Gemcitabine, Cisplatin, And Bevacizumab to Gemcitabine, Cisplatin, and Placebo in Patients With Advanced Transitional Cell Carcinoma	GI Tract Cancer
E1505 - A Phase III Randomized Trial of Adjuvant Chemotherapy With or Without Bevacizumab for Patients with Completely Resected Stage IB (Y4cm)-IIIA Non-Small Cell Lung Cancer (NSCLC)	Lung Cancer
E1609 (Cancer Trial) - A Phase III Randomized Study of Adjuvant Ipilimumab Anti-CTLA4 Therapy Versus High-Dose Interferon Alfa-2b for Resected High-risk Melanoma	Melanoma Cancer Trial
E1908 - A Phase II Randomized Trial Comparing Standard and Low Dose Rituximab: Initial Treatment of Progressive Chronic Lymphocytic Leukemia in Elderly Patients using Alemtuzumab, and Rituximab	Leukemia Cancer Trial
E2108 - A Randomized Phase III Trial of the Value of Early Local Therapy for the Intact Primary Tumor in Patients with Metastatic Breast Cancer	Breast Cancer
E2809 - A Phase II, Randomized Study of MK-2206 - Bicalutamide Combination in Patients With Rising PSA at High-Risk of Progression After Primary Therapy	Prostate Cancer
E2810 - Randomized, Double-Blind Phase III Study of Pazopanib vs. Placebo in Subjects with Metastatic Renal Cell Carcinoma Who Have No Evidence of Disease Following Metastasectomy	Renal Cell Carcinoma Cancer Trial
E3108 - A Phase II Prospective Trial Correlating Progression Free Survival with CYP2D6 Activity in Patients with Metastatic Breast Cancer Treated with Single Agent Tamoxifen	Breast Cancer
E3508: A Phase II Randomized Trial of Paclitaxel, Carboplatin, Bevacizumab with or without IMC-A12 in Patients with Advanced Non-Squamous, Non-Small Cell Lung Cancer	Lung Cancer
E3611 - A Randomized Phase II Study of Ipilimumab at 3 mg/kg or 10 mg/kg Alone or in Combination with High Dose Interferon-a in Advanced Melanoma	Melanoma Cancer Trial
E3A06 - Randomized Phase 11//III Trial of Lenalidomide Versus Observation Alone in Patients with Asymptomatic High-Risk Smoldering Multiple Myeloma	Myeloma Cancer Trial
E4805 - A Randomized Phase II Study to Determine the Effect of-2 Different Doses of AVE0005 (VEGF Trap) in Patients with Metastatic Renal Cell Carcinoma	Renal Cell Carcinoma Cancer Trial
E5508 - Randomized Phase III Study of Maintenance Therapy with Bevacizumab, Pemetrexed, or a Combination of Bevacizumab and Pemetrexed Following Carboplatin, Paclitaxel and Bevacizumab for Advanced Non-Squamous NSCLC	Lung Cancer
GOG 0186K - A Randomized phase II study of NCI SUPPLIED cabozantinib (NSC #761968 IND #116059) versus weekly paclitaxel (NSC #673089) in the treatment of persistent or recurrent epithelial ovarian, fallopian tube or primary peritoneal cancer	Gynecological Cancer
GOG 0225 - Can Diet and Physical Activity Modulate Ovarian, Fallopian Tube and Primary Peritoneal Cancer Progression-Free Survival?	Gynecological Cancer
GOG 0238 - A Randomized Phase II Trial Of Pelvic Irradiation With Or Without Concurrent Weekly Cisplatin In Patients With Pelvic-Only Recurrence Of Carcinoma Of The Uterine Corpus	Gynecological Cancer
GOG 0241 - A GCIG INTERGROUP MULTICENTER TRIAL OF OPEN LABEL CARBOPLATIN AND PACLITAXEL +/- BEVACIZUMAB COMPARED WITH OXALIPLATIN & CAPECITABINE +/- BEV AS 1st LINE CHEMOTHERAPY IN PATIENTS WITH MUCINOUS EPITHELIAL OVARIAN OR FALLOPIAN TUBE CANCER	Gynecological Cancer
GOG 0244 -The Lymphedema and Gynecologic Cancer (Leg) Study: Incidence, Risk Factors, and Impact in Newly Diagnosed Patients	Gynecological Cancer
GOG 0244 -The Lymphedema and Gynecologic Cancer (Leg) Study: Incidence, Risk Factors, and Impact in Newly Diagnosed Patients	Gynecological Cancer
GOG 0244 -The Lymphedema and Gynecologic Cancer (Leg) Study: Incidence, Risk Factors, and Impact in Newly Diagnosed Patients	Gynecological Cancer
GOG 0258 - A RANDOMIZED PHASE III TRIAL OF CISPLATIN AND TUMOR VOLUME DIRECTED	Gynecological Cancer
GOG 0261 - A Randomized Phase III Trial of Paclitaxel Plus Carboplatin Versus Ifosfamide Plus Paclitaxel in Chemotherapy-Naïve Patients With Newly Diagnosed Stage I – IV or Persistent or Recurrent Carcinosarcoma (Mixed Mesodermal Tumors) of the Uterus or	Gynecological Cancer
GOG 0263 - A Randomized Phase III Clinical Trial of Adjuvant Radiation Versus Chemoradiation in Intermediate Risk, Stage I/IIa Cervical Cancer Treated with Initial Radical Hysterectomy and Pelvic Lymphadenectomy	Gynecological Cancer
GOG 0273 - Chemotherapy Toxicity in Elderly Women with Ovarian, Primary Peritoneal, or Fallopian Tube Cancer	Gynecological Cancer
GOG 0275 - A Phase III Randomized Trial of Pulse Actinomycin-D Versus Multi-Day Methotrexate for the Treatment of Low-Risk Gestational Trophoblastic Neoplasia	Gynecological Cancer
GOG 0279: A PHASE II TRIAL EVALUATING CISPLATIN (NSC #119875) AND GEMCITABINE (NSC #613327) CONCURRENT WITH INTENSITY-MODULATED RADIATION THERAPY (IMRT) IN THE TREATMENT OF LOCALLY ADVANCED SQUAMOUS CELL CARCINOMA OF THE VULVA	Gynecological Cancer
IM-T-hA20-08 - Phase I/II Study of Immunotherapy with Subcutaneously Administered Veltuzumab (hA20) in Patients with CD20+ Non-Hodgkin’s Lymphoma or Chronic Lymphocytic Leukemia	Leukemia Cancer Trial
N0574 - Phase III Randomized Trial of the Role of Whole Brain Radiation Therapy in Addition to Radiosurgery in Patients with One to Three Cerebral Metastases	Head & Neck Cancer
NSABP B-43 - A Phase III Clinical Trial Comparing Trastuzumab Given Concurrently with Radiation Therapy and Radiation Therapy Alone for Women with HER2-Positive Ductal Carcinoma in Situ Resected by Lumpectomy	Breast Cancer
NSABP B-47 - Chemotherapy With or Without Trastuzumab After Surgery in Treating Women With Invasive Breast Cancer	Breast Cancer
NSABP B-49: A Phase III Clinical Trial Comparing the Combination of Docetaxel Plus Cyclophosphamide to Anthracycline-Based Chemotherapy Regimens for Women with Node-Positive or High-Risk Node-Negative, HER2-Negative Breast Cancer	Breast Cancer
NSABP P5: Phase III - Statin Polyp Prevention Trial in Patients with Resected Colon Cancer	Colorectal Cancer
RTOG 0436 - A Phase III Trial Evaluating the Addition of Cetuximab to Paclitaxel, Cisplatin and Radiation for Patients With Esophageal Cancer Who Are Treated Without Surgery	GI Tract Cancer
RTOG 0534- A Phase III Trial Of Short Term Androgen Deprivation With Pelvic Lymph Node Or Prostate Bed Only Radiotherapy (SPPORT) In Prostate Cancer Patients With A Rising PSA After Radical Prostatectomy	Prostate Cancer
RTOG 0724 - Phase III Randomized Study of Concurrent Chemotherapy and Pelvic Radiation Therapy With or Without Adjuvant Chemotherapy in High-Risk Patients With Early-Stage Cervical Carcinoma Following Radical Hysterectomy.	Gynecological Cancer
RTOG 0848 - A Phase III Trial Evaluating Both Erlotinib and Chemoradiation as Adjuvant Treatment for Patients with Resected Head of Pancreas Adenocarcinoma	Pancreatic Cancer
RTOG 0920 - A Phase III study of postoperative radiation therapy (imrt) +/- cetuximab for locally-advanced resected head and neck cancer	Head & Neck Cancer
RTOG 0937 - Randomized Phase II Study Comparing Prophylactic Cranial Irradiation Alone to Prophylactic Cranial Irradiation and Consolidative Extra-Cranial Irradiation for Extensive Disease Small Cell Lung Cancer (ED-SCLC)	Lung Cancer
RTOG 1005 - A Phase III Trial of Accelerated Whole Breast Irradiation with Hypofractionation Plus Concurrent Boost Versus Standard Whole Breast Irradiation Plus Sequential Boost for Early-Stage Breast Cancer	Breast Cancer
RTOG 1010 - A PHASE III TRIAL EVALUATING THE ADDITION OF TRASTUZUMAB TO TRIMODALITY TREATMENT OF HER2-OVEREXPRESSING ESOPHAGEAL ADENOCARCINOMA	GI Tract Cancer
RTOG 1012 - PHASE II RANDOMIZED TRIAL OF PROPHYLACTIC MANUKA HONEY FOR THE REDUCTION OF CHEMORADIATION THERAPY INDUCED ESOPHAGITIS- RELATED PAIN DURING THE TREATMENT OF LUNG CANCER	Lung Cancer
RTOG 1016 - Phase III Trial of Radiotherapy Plus Cetuximab versus Chemoradiotherapy in HPV-Associated Oropharynx Cancer	Head & Neck Cancer
RTOG 1203 - A Randomized Phase III Study Of Standard vs. IMRT Pelvic Radiation For Post-Operative Treatment of Endometrial and Cervical Cancer (Time-C)	Gynecological Cancer
S0820-A Double Blind Placebo-Controlled Trial of Eflornithine & Sulindac (E&S) to Prevent Recurrence of High Risk Adenomas & 2nd Primary Colorectal Cancers in Patients with Stage 0-III Colon Cancer, Phase III - Preventing Adenomas of the Colon with E & S	Colorectal Cancer
S1007 - A Phase III Randomized Clinical Trial of Standard Adjuvant Endocrine Therapy +/- Chemotherapy in Patients with 1-3 Positive Nodes, Hormone Receptor-Positive and HER2-Negative Breast Cancer with Recurrence Score (RS) of 25 or Less.	Breast Cancer
S1115 - A Randomized Phase II Clinical Trial of AZD6244 Hydrogen Sulfate (NSC-748727) and MK-2206 (Nsc-749607) vs. Mfolfox in Patients with Metastatic Pancreatic Cancer after Prior Chemotherapy	Pancreatic Cancer
SCUSF 0806 (Suncoast) - “Phase II placebo-controlled trial of lisinopril and Coreg CR® to reduce cardiotoxicity in patients with breast cancer receiving (neo)adjuvant chemotherapy with trastuzumab (Herceptin®)	Breast Cancer